Reducing infection risk and improve wound healing.

That is what the technology can offer. A unique approach in times where antibiotics are loosing their effectiveness due to resistant bacteria.

 

Reducing infection risks.

A pre-clinical trail with an permanent implant made with Saniconcentrate™ resulted in a scientific medical publication revealing a significant infection reduction on specimens with an implant made with Saniconcentrate™ compared to the specimens with a normal implant.


Improving wound healing.

Experiments with wound patches made with Saniconcentrate™ reveal a significant faster wound healing with these patients than normally expected. More details will follow later.






Examples.

Parx technology reduces infection in surgery with hernia mesh for abdominal wall repair.


Parx Materials announced a medical publication of a pre-clinical study with a permanent implant. ‘Zinc-Impregnated Mesh for Abdominal Wall Repair Reduces Infection in a Rat Model of Peritonitis’ is the title of the study published by The Journal of Surgical Research on October 24th, 2019. The study was carried out by a.o. the Erasmus University Medical Center in Rotterdam, The Netherlands using polypropylene meshes produced with and without the aid of the Parx Materials antimicrobial and anti-biofilm technology. 







Hernia
A hernia is a condition in which part of the intestine bulges through a weak area in the abdominal muscles. Hernias can cause pain and discomfort in the patient, and in more severe cases, can even cause the twisting of the intestine, which would subsequently require removal. Hernia repair involves re-positioning the intestine into the body cavity. It is one of the most commonly performed procedures in Europe and the U.S. and there is a rising demand for hernia repair solutions as the condition is intrinsically linked to the growing elderly and obese populations.
 
Bacteria is the largest threat
It occurs regularly that a gastrointestinal surgeon needs to operate on a patient twice. Mesh infection is one of the most severe and disastrous complications after hernia repair and may require surgical removal of the implanted mesh. Mesh removal may lead to patient morbidity, prolonged hospital admission, and increasing healthcare costs. Bacterial attachment and proliferation are necessary steps in the development of infection depending on several factors, such as the type of polymer and its structure. With the Parx Materials technology, it was found that it is able to inhibit multiple activities of bacteria. 
 
Study
The objective of the study performed by the Erasmus University Medical Center was to assess whether a polypropylene mesh produced with the Parx technology has better antibacterial properties in a heavily contaminated environment compared with a regular polypropylene mesh. After a follow-up of 90 days a significant lower bacteria count was found in the mesh fitted with the Parx technology. 
 

Food packaging with Saniconcentrate™:
fresh for longer and no more bad odor.


EU AND US FOOD CONTACT COMPLIANCE CONFIRMED

Zwiers Regulatory Consultancy finalised its evaluation of the safety and compliance of Saniconcentrate™ in food contact applications according to EU and US regulations.
 
To proof food contact material compliance with EU and US regulation, research has been done for each substance within Saniconcentrate™. Moreover, to proof safety for each of them, regulation and databases of food additives, cosmetic ingredients, handbook of pharmaceutical excipients, CLP regulation (to ensure a high level of protection of health and the environment), regulatory agencies inventories and other sources such REACH, Pesticide and Plant protection product regulation have been consulted.